Mannose binding lectin genes (MBL2) polymorpshisms and the periodontal disease in diabetic patients
نویسندگان
چکیده
منابع مشابه
Evaluation of Serum Levels of Mannose Binding Lectin-2, Tenascin-C in Patients with Coronary Artery Disease (CAD)
Cardiovascular disease (CVD) is a leading cause of death worldwide and continues to increase in prevalence compared to previous decades, in part because of the aging of the world population. Atherosclerotic CVD starts at a very young age and progresses over time allowing sufficient time for screening and early detection of the condition. Advances in biomarker research and developments related t...
متن کاملP 144: Sunflower Mannose binding Lectin-Associated Serine Protease Inhibitor-1 (SFMI-1) and -2: Significant Inhibitors of Mannose binding Lectin Pathway which Helps in Multiple Sclerosis Treatment
One of the important parts of innate immunity is complement system that occurs in three different ways; the classic, the alternative and the lectin pathway. The four pattern recognition molecules that have been identified till now are Mannose binding lectin (MBL), a component of lectin pathway, and three ficolins (ficolin1,-2 and -3) which compound to the carbohydrates of the cell surface. MBL ...
متن کاملAssociation of Levels of Mannose-Binding Lectin and the MBL2 Gene with Type 2 Diabetes and Diabetic Nephropathy
OBJECTIVE To investigate the association of Mannose-binding lectin (MBL) and the MBL2 gene with type 2 diabetes and diabetic nephropathy and the influence of MBL2 polymorphisms on serum MBL levels. METHODS The study population included 675 type 2 diabetic patients with or without nephropathy and 855 normoglycemic controls. The single nucleotide polymorphisms (SNPs) of rs1800450, rs1800451, an...
متن کاملPolymorphisms in the Mannose-Binding Lectin Gene are Associated with Defective Mannose-Binding Lectin Functional Activity in Crohn’s Disease Patients
Mannose-binding lectin, together with mannose-associated serine proteases, activates the lectin pathway of the complement system and subsequent inflammatory mechanisms. An association between mannose-binding lectin deficiency and anti-Saccharomyces cerevisiae antibody levels is observed in Crohn's disease and this deficiency is frequently associated with a severe Crohn's disease phenotype. In t...
متن کاملRole of mannose-binding lectin (MBL2) genotyping in predicting the risk of recurrent otitis media (rOM).
Otitis media (OM) is the most common childhood disease. Almost all children experience at least one episode of otitis media with effusion (OME) or acute otitis (OMA) during childhood, and a substantial subgroup is confronted with recurrent episodes. If not treated adequately, OM may lead to temporary or permanent hearing loss. It is well known that bacteria and viruses cause OMA, and may play a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Revista Odonto Ciência (Online)
سال: 2011
ISSN: 1980-6523
DOI: 10.1590/s1980-65232011000300002